At the heart of that difference are their active ingredients: empagliflozin in Jardiance and semaglutide in Ozempic
Technically, some of their manufacturers are supposed to cease production immediately
Medical guidelines, drug availability, insurance policies, and telehealth regulations change frequently
Most significantly for weight management, semaglutide acts on receptors in the brain's appetite centres, particularly in the hypothalamus, reducing hunger signals and food cravings
SUSTAIN-6 (semaglutide) showed acute pancreatitis in 0.3% of semaglutide patients versus 0.2% of placebo patients
Furthermore, retatrutide has shown unprecedented efficacy in addressing MASLD/MASH